Factor VII Deficiency

Factor VII (7) deficiency is an inherited bleeding disorder caused when a person's body does not produce enough of a protein in the blood (factor VII or FVII) that helps blood clot or the factor VII doesn't work properly. The disorder is rare, affecting one in 500,000 people.

A non-inherited type of factor VII deficiency may also be acquired through liver disease, low levels of vitamin K, or from other problems with absorption. It can also develop in people who take coumadin, a medication that prevents blood clotting.

Links to selected resources:

What Is Factor VII Deficiency?
(World Federation of Hemophilia)
See the About Bleeding Disorders section. Explains the causes of this blood disorder, its symptoms, diagnosis and treatment.

Factor VII deficiency
(Canadian Hemophilia Society, 2001)
This booklet describes factor VII deficiency, what causes it, how it is passed on, severity, diagnosis, symptoms, treatments, specific problems for women, healthy living and preventing bleeds.

Factor VII deficiency
(National Hemophilia Foundation, USA)

Source: What are rare clotting factor deficiencies? World Federation of Hemophilia, Montreal, Canada, 2009.

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Date last reviewed: 21 September 2020