Factor I Deficiency

Factor I (1) or fibrinogen deficiency is an inherited bleeding disorder caused when a person's body does not produce any or enough of a protein in the blood (fibrinogen) that plays an important role in blood clotting or the fibrinogen doesn't work properly. It is very rare and often found in people whose parents are blood relatives.

Links to selected resources:

What Is Factor I (Fibrinogen) Deficiency?
(World Federation of Hemophilia, 2012)
See the About > Bleeding Disorders section.
Explains the causes of Factor I deficiency, its symptoms, diagnosis and treatment.

Factor I deficiency (Fibrinogen deficiency)
(Canadian Hemophilia Society, 2004)
A comprehensive booklet covering types of fibrinogen deficiency, causes, inheritance, symptoms, treatments, prevention, special precautions and specific problems for women.

Factor I deficiency
(National Hemophilia Foundation, USA)

Source: What are rare clotting factor deficiencies? World Federation of Hemophilia, Montreal, Canada, 2009.

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Date last reviewed: 18 September 2020